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Multiple receptor tyrosine kinases promote the in vitro phenotype of metastatic human osteosarcoma cell lines
The survival rate for osteosarcoma patients with localized disease is 70% and only 25% for patients with metastases. Therefore, novel therapeutic and prognostic tools are needed. In this study, extensive screening and validation strategies identified Axl, EphB2, FGFR2, IGF-1R and Ret as specific rec...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511679/ https://www.ncbi.nlm.nih.gov/pubmed/23552467 http://dx.doi.org/10.1038/oncsis.2012.34 |