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Genomic aberrations in normal tissue adjacent to HER2-amplified breast cancers: field cancerization or contaminating tumor cells?

Field cancerization effects as well as isolated tumor cell foci extending well beyond the invasive tumor margin have been described previously to account for local recurrence rates following breast conserving surgery despite adequate surgical margins and breast radiotherapy. To look for evidence of...

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Detalles Bibliográficos
Autores principales: Sadanandam, Anguraj, Lal, Aseem, Benz, Stephen C., Eppenberger-Castori, Serenella, Scott, Gary, Gray, Joe W., Spellman, Paul, Waldman, Fred, Benz, Christopher C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511697/
https://www.ncbi.nlm.nih.gov/pubmed/23104223
http://dx.doi.org/10.1007/s10549-012-2290-3