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Downregulation of gastrokine-1 in gastric cancer tissues and restoration of its expression induced gastric cancer cells to apoptosis

BACKGROUND: Gastrokine-1 (GKN1), a secreted protein, is specifically expressed in gastric mucosa to protect and maintain the integrity of gastric epithelium. The present study investigated differential expression of GKN1 in normal, precancerous, and cancerous gastric tissues, and explored the biolog...

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Detalles Bibliográficos
Autores principales: Mao, Wei, Chen, Jie, Peng, Tie-Li, Yin, Xiao-Fei, Chen, Lian-Zhou, Chen, Min-Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511871/
https://www.ncbi.nlm.nih.gov/pubmed/22621392
http://dx.doi.org/10.1186/1756-9966-31-49