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Downregulation of gastrokine-1 in gastric cancer tissues and restoration of its expression induced gastric cancer cells to apoptosis
BACKGROUND: Gastrokine-1 (GKN1), a secreted protein, is specifically expressed in gastric mucosa to protect and maintain the integrity of gastric epithelium. The present study investigated differential expression of GKN1 in normal, precancerous, and cancerous gastric tissues, and explored the biolog...
Autores principales: | Mao, Wei, Chen, Jie, Peng, Tie-Li, Yin, Xiao-Fei, Chen, Lian-Zhou, Chen, Min-Hu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511871/ https://www.ncbi.nlm.nih.gov/pubmed/22621392 http://dx.doi.org/10.1186/1756-9966-31-49 |
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