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SNP-set analysis replicates acute lung injury genetic risk factors

BACKGROUND: We used a gene – based replication strategy to test the reproducibility of prior acute lung injury (ALI) candidate gene associations. METHODS: We phenotyped 474 patients from a prospective severe trauma cohort study for ALI. Genomic DNA from subjects’ blood was genotyped using the IBC ch...

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Detalles Bibliográficos
Autores principales: Meyer, Nuala J, Daye, Zhongyin John, Rushefski, Melanie, Aplenc, Richard, Lanken, Paul N, Shashaty, Michael GS, Christie, Jason D, Feng, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512475/
https://www.ncbi.nlm.nih.gov/pubmed/22742663
http://dx.doi.org/10.1186/1471-2350-13-52