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Fibronectin glycation increases IGF-I induced proliferation of human aortic smooth muscle cells

The advanced glycation end products, namely AGEs, contribute to long-termed complications of diabetes mellitus, including macroangiopathy, where smooth muscle cells (SMC) proliferation stimulated by platelet-derived growth factor (PDGF) isoforms and insulin-like growth factor-I (IGF-I) plays an impo...

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Detalles Bibliográficos
Autores principales: Corrêa-Giannella, Maria Lúcia, de Azevedo, Maria Regina Andrade, LeRoith, Derek, Giannella-Neto, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512496/
https://www.ncbi.nlm.nih.gov/pubmed/22553932
http://dx.doi.org/10.1186/1758-5996-4-19