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A cooperative strategy for parameter estimation in large scale systems biology models

BACKGROUND: Mathematical models play a key role in systems biology: they summarize the currently available knowledge in a way that allows to make experimentally verifiable predictions. Model calibration consists of finding the parameters that give the best fit to a set of experimental data, which en...

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Detalles Bibliográficos
Autores principales: Villaverde, Alejandro F, Egea, Jose A, Banga, Julio R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512509/
https://www.ncbi.nlm.nih.gov/pubmed/22727112
http://dx.doi.org/10.1186/1752-0509-6-75