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Getting DNA copy numbers without control samples

BACKGROUND: The selection of the reference to scale the data in a copy number analysis has paramount importance to achieve accurate estimates. Usually this reference is generated using control samples included in the study. However, these control samples are not always available and in these cases,...

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Detalles Bibliográficos
Autores principales: Ortiz-Estevez, Maria, Aramburu, Ander, Rubio, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512512/
https://www.ncbi.nlm.nih.gov/pubmed/22898240
http://dx.doi.org/10.1186/1748-7188-7-19