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Control and inhibition analysis of complex formation processes

BACKGROUND: Proteolytic degradation of the extracellular matrix (ECM) is a key event in tumour metastasis and invasion. Matrix metalloproteinases (MMPs) are a family of endopeptidases that degrade most of the components of the ECM. Several broad-spectrum MMP inhibitors (MMPIs) have been developed, b...

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Detalles Bibliográficos
Autores principales: Saitou, Takashi, Itano, Keiko, Hoshino, Daisuke, Koshikawa, Naohiko, Seiki, Motoharu, Ichikawa, Kazuhisa, Suzuki, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512525/
https://www.ncbi.nlm.nih.gov/pubmed/22863329
http://dx.doi.org/10.1186/1742-4682-9-33