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512 MUTANT IL-3: A Common Down Regulator for Components of IGE Mediated Signal Transduction Pathway

BACKGROUND: FcepsilonRI mediated signal pathway in basophils and mast cells leads to release of histamine and other mediators. Interestingly, basophils from 10% to 20% of the population do not release histamine and other mediators on activation of the IgE signal transduction pathway and this has bee...

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Detalles Bibliográficos
Autores principales: Singh, Anand, Singh, A.B., Kumar, Pawan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Allergy Organization Journal 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512784/
http://dx.doi.org/10.1097/01.WOX.0000411627.78925.17