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121 Ovalbumin-induced Bronchial Asthma is Compromised in Apoptosis Signal-Regulating Kinase-Deficient Mice

BACKGROUND: Apoptosis signal-regulating kinase 1 (ASK1), a member of mitogen –activated protein (MAP) kinase kinase kinases (MAP3Ks) protein family, plays a crucial role in the induction of apoptosis and inflammation in some cell types. Allergic asthma is a chronic inflammatory airway disease charac...

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Detalles Bibliográficos
Autores principales: Mizuguchi, Junichiro, Furuhata, Masae, Ichijo, Hidenori, Takada, Eiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Allergy Organization Journal 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512814/
http://dx.doi.org/10.1097/01.WOX.0000411866.51255.77