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260 Association Between Genetic Polymorphisms of ABCC2 Transporter and the Susceptibility to Maculopapular Eruption Induced by Antituberculosis Drugs

BACKGROUND: ATP-binding cassette (ABC) transporter proteins play an important role in drug disposition. Polymorphisms of ABC transporter genes (ABCC2 and ABCB1) may be risk markers for maculopapular eruption (MPE) induced by unusual accumulation of antituberculosis drugs (ATD) itself or metabolites....

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Detalles Bibliográficos
Autores principales: Kim, Sang-Hoon, Kim, Sang-Heon, Lee, Jae-Hyung, Lee, Byoung-Hoon, Jee, Young-Koo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Allergy Organization Journal 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512837/
http://dx.doi.org/10.1097/01.WOX.0000412017.99479.f7