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94 High Immunogenicity of the Allergen PHL P 5 Expressed in Transgenic Mice as a Membrane-anchored Protein

BACKGROUND: Induction of long-term tolerance towards Phl p 5 was previously achieved by transplantation of hematopoetic stem cells (HSCs) genetically modified to express membrane-bound Phl p 5 allergen. To facilitate the further development of tolerogenic cell therapies for allergy, a transgenic mou...

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Detalles Bibliográficos
Autores principales: Farkas, Andreas, Baranyi, Ulrike, Valenta, Rudolf, Wekerle, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Allergy Organization Journal 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512942/
http://dx.doi.org/10.1097/01.WOX.0000411839.09657.43