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42 Polyprenol Could Prevent Loss of Filaggrin in Epithelial Cells in Atopic Dermatitis

BACKGROUND: In epithelial cells loss of filaggrin correlates with atopic dermatitis (AD) presence and activity. Dysregulation of DPAGT1 (Dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) causes disturbances in filaggrin expression. The rese...

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Detalles Bibliográficos
Autores principales: Kuznecovs, Ivans S., Joksta, Inese, Kuznecovs, Sergejs, Kuznecovac, Galina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Allergy Organization Journal 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513015/
http://dx.doi.org/10.1097/01.WOX.0000411787.97837.23