126 Creation of a Humanized Model for Respiratory Allergy Using a Human Mugwort-specificT-Cell Receptor and HLA-DR1
BACKGROUND: Currently, T cell receptor (TCR) transgenic (tg) mice with a murine TCR specific for chicken ovalbumin in the context of a murine restriction element (I-A(d)) are frequently used in allergy research to investigate T helper cell differentiation and allergy treatment in vivo. METHODS: We h...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
World Allergy Organization Journal
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513154/ http://dx.doi.org/10.1097/01.WOX.0000411871.74126.3c |