126 Creation of a Humanized Model for Respiratory Allergy Using a Human Mugwort-specificT-Cell Receptor and HLA-DR1

BACKGROUND: Currently, T cell receptor (TCR) transgenic (tg) mice with a murine TCR specific for chicken ovalbumin in the context of a murine restriction element (I-A(d)) are frequently used in allergy research to investigate T helper cell differentiation and allergy treatment in vivo. METHODS: We h...

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Autores principales: Neunkirchner, Alina, Mager, Lukas, Reichl, Victoria, Schmetterer, Klaus, Haiderer, Daniela, Rosloniec, Edward, Naumann, Ronald, Jahn-Schmid, Beatrice, Bohle, Barbara, Pickl, Winfried F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Allergy Organization Journal 2012
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513154/
http://dx.doi.org/10.1097/01.WOX.0000411871.74126.3c