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Pharmacogenetics of rheumatoid arthritis: Potential targets from susceptibility genes and present therapies

Rheumatoid arthritis (RA) is a chronic heterogeneous autoimmune disorder of unknown etiology resulting in inflammation in the synovium, cartilage, and bone. Genetic factors play an important role in susceptibility to RA as the heritability of RA is between 50% and 60%, with the human leukocyte antig...

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Detalles Bibliográficos
Autores principales: O’Rielly, Darren D, Rahman, Proton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513198/
https://www.ncbi.nlm.nih.gov/pubmed/23226040