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ERCC1 and XRCC1 as biomarkers for lung and head and neck cancer

Advanced stage non-small cell lung cancer and head and neck squamous cell carcinoma are both treated with DNA damaging agents including platinum-based compounds and radiation therapy. However, at least one quarter of all tumors are resistant or refractory to these genotoxic agents. Yet the agents ar...

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Detalles Bibliográficos
Autores principales: Vaezi, Alec, Feldman, Chelsea H, Niedernhofer, Laura J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513219/
https://www.ncbi.nlm.nih.gov/pubmed/23226053
http://dx.doi.org/10.2147/PGPM.S20317