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Drug targets and predictive biomarkers in the management of metastatic melanoma

Melanoma is the leading cause of fatal skin cancer, and in the past few decades, there has been an increase in the incidence of and mortality from metastatic melanoma. Until recently, the therapeutic options for treatment of metastatic melanoma were limited. The approval of ipilimumab (an anti-CTLA-...

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Detalles Bibliográficos
Autores principales: Thumar, Jaykumar, Giesen, Eva, Kluger, Harriet M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513235/
https://www.ncbi.nlm.nih.gov/pubmed/23226069
http://dx.doi.org/10.2147/PGPM.S25100