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Assessment of Benzene-Induced Hematotoxicity Using a Human-Like Hematopoietic Lineage in NOD/Shi-scid/IL-2Rγ(null) Mice

Despite recent advancements, it is still difficult to evaluate in vivo responses to toxicants in humans. Development of a system that can mimic the in vivo responses of human cells will enable more accurate health risk assessments. A surrogate human hematopoietic lineage can be established in NOD/Sh...

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Detalles Bibliográficos
Autores principales: Takahashi, Masayuki, Tsujimura, Noriyuki, Yoshino, Tomoko, Hosokawa, Masahito, Otsuka, Kensuke, Matsunaga, Tadashi, Nakasono, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513313/
https://www.ncbi.nlm.nih.gov/pubmed/23226520
http://dx.doi.org/10.1371/journal.pone.0050448