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Signaling Dependent and Independent Mechanisms in Pemphigus Vulgaris Blister Formation

Pemphigus vulgaris (PV) is an autoimmune epidermal blistering disease caused by autoantibodies directed against the desmosomal cadherin desmoglein-3 (Dsg3). Significant advances in our understanding of pemphigus pathomechanisms have been derived from the generation of pathogenic monoclonal Dsg3 anti...

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Detalles Bibliográficos
Autores principales: Saito, Masataka, Stahley, Sara N., Caughman, Christopher Y., Mao, Xuming, Tucker, Dana K., Payne, Aimee S., Amagai, Masayuki, Kowalczyk, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513318/
https://www.ncbi.nlm.nih.gov/pubmed/23226536
http://dx.doi.org/10.1371/journal.pone.0050696