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Pretreatment data is highly predictive of liver chemistry signals in clinical trials

PURPOSE: The goal of this retrospective analysis was to assess how well predictive models could determine which patients would develop liver chemistry signals during clinical trials based on their pretreatment (baseline) information. PATIENTS AND METHODS: Based on data from 24 late-stage clinical tr...

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Detalles Bibliográficos
Autores principales: Cai, Zhaohui, Bresell, Anders, Steinberg, Mark H, Silberg, Debra G, Furlong, Stephen T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513908/
https://www.ncbi.nlm.nih.gov/pubmed/23226004
http://dx.doi.org/10.2147/DDDT.S34271