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Pretreatment data is highly predictive of liver chemistry signals in clinical trials
PURPOSE: The goal of this retrospective analysis was to assess how well predictive models could determine which patients would develop liver chemistry signals during clinical trials based on their pretreatment (baseline) information. PATIENTS AND METHODS: Based on data from 24 late-stage clinical tr...
Autores principales: | Cai, Zhaohui, Bresell, Anders, Steinberg, Mark H, Silberg, Debra G, Furlong, Stephen T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513908/ https://www.ncbi.nlm.nih.gov/pubmed/23226004 http://dx.doi.org/10.2147/DDDT.S34271 |
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