The importance of serine 776 in Ataxin-1 partner selection: A FRET Analysis

Anomalous expansion of a polymorphic tract in Ataxin-1 causes the autosomal dominant spinocerebellar ataxia type 1. In addition to polyglutamine expansion, requirements for development of pathology are phosphorylation of serine 776 in Ataxin-1 and nuclear localization of the protein. The phosphoryla...

Descripción completa

Detalles Bibliográficos
Autores principales: Menon, Rajesh P., Soong, Daniel, de Chiara, Cesira, Holt, Mark R., Anilkumar, Narayana, Pastore, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513968/
https://www.ncbi.nlm.nih.gov/pubmed/23213356
http://dx.doi.org/10.1038/srep00919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513968/
https://www.ncbi.nlm.nih.gov/pubmed/23213356
http://dx.doi.org/10.1038/srep00919

Ejemplares similares