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Open chromatin structures regulate the efficiencies of pre-RC formation and replication initiation in Epstein-Barr virus
Whether or not metazoan replication initiates at random or specific but flexible sites is an unsolved question. The lack of sequence specificity in origin recognition complex (ORC) DNA binding complicates genome-scale chromatin immunoprecipitation (ChIP)-based studies. Epstein-Barr virus (EBV) persi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514025/ https://www.ncbi.nlm.nih.gov/pubmed/22891264 http://dx.doi.org/10.1083/jcb.201109105 |