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Open chromatin structures regulate the efficiencies of pre-RC formation and replication initiation in Epstein-Barr virus

Whether or not metazoan replication initiates at random or specific but flexible sites is an unsolved question. The lack of sequence specificity in origin recognition complex (ORC) DNA binding complicates genome-scale chromatin immunoprecipitation (ChIP)-based studies. Epstein-Barr virus (EBV) persi...

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Detalles Bibliográficos
Autores principales: Papior, Peer, Arteaga-Salas, José M., Günther, Thomas, Grundhoff, Adam, Schepers, Aloys
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514025/
https://www.ncbi.nlm.nih.gov/pubmed/22891264
http://dx.doi.org/10.1083/jcb.201109105