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Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes

Rab proteins are important regulators of insulin-stimulated GLUT4 translocation to the plasma membrane (PM), but the precise steps in GLUT4 trafficking modulated by particular Rab proteins remain unclear. Here, we systematically investigate the involvement of Rab proteins in GLUT4 trafficking, focus...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Wang, Yan, Zhang, Jinzhong, Deng, Yongqiang, Jiang, Li, Song, Eli, Wu, Xufeng S., Hammer, John A., Xu, Tao, Lippincott-Schwartz, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514028/
https://www.ncbi.nlm.nih.gov/pubmed/22908308
http://dx.doi.org/10.1083/jcb.201111091