Mena binds α5 integrin directly and modulates α5β1 function

Mena is an Ena/VASP family actin regulator with roles in cell migration, chemotaxis, cell–cell adhesion, tumor cell invasion, and metastasis. Although enriched in focal adhesions, Mena has no established function within these structures. We find that Mena forms an adhesion-regulated complex with α5β...

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Detalles Bibliográficos
Autores principales: Gupton, Stephanie L., Riquelme, Daisy, Hughes-Alford, Shannon K., Tadros, Jenny, Rudina, Shireen S., O.Hynes, Richard, Lauffenburger, Douglas, Gertler, Frank B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514034/
https://www.ncbi.nlm.nih.gov/pubmed/22908313
http://dx.doi.org/10.1083/jcb.201202079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514034/
https://www.ncbi.nlm.nih.gov/pubmed/22908313
http://dx.doi.org/10.1083/jcb.201202079

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