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Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse

This report describes the clinical courses of two acute myeloid leukemia patients. Both had MLL translocations, the first a t(10;11)(p11.2;q23) with MLL-AF10 and the second a t(11;19)(q23;p13.1) with MLL-ELL fusion. They achieved a clinical remission under conventional chemotherapy but relapsed shor...

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Detalles Bibliográficos
Autores principales: Burmeister, Thomas, Molkentin, Mara, Meyer, Claus, Lachmann, Nils, Schwartz, Stefan, Friedrichs, Birte, Beyer, Jörg, Blau, Igor Wolfgang, Lohm, Gunnar, Tietze-Bürger, Carola, Marschalek, Rolf, Uharek, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514080/
https://www.ncbi.nlm.nih.gov/pubmed/23211007
http://dx.doi.org/10.1186/2162-3619-1-6