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Ratio of involved/uninvolved immunoglobulin quantification by Hevylite™ assay: clinical and prognostic impact in multiple myeloma

BACKGROUND: HevyLite™ is a new, recently developed method that facilitates separate quantification of the kappa- and lambda-bounded amounts of a given immunoglobulin (Ig). Using this method, we measured intact immunoglobulin (heavy/light chain; HLC) IgG-kappa, IgG-lambda, IgA-kappa, IgA-lambda indiv...

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Detalles Bibliográficos
Autores principales: Koulieris, Efstathios, Panayiotidis, Panayiotis, Harding, Stephen J, Kafasi, Nikolitsa, Maltezas, Dimitris, Bartzis, Vassiliki, Tzenou, Tatiana, Dimou, Maria, Georgiou, George, Mirbahai, Ladan, Bradwell, Arthur R, Kyrtsonis, Marie-Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514091/
https://www.ncbi.nlm.nih.gov/pubmed/23211046
http://dx.doi.org/10.1186/2162-3619-1-9