BIRC6 (APOLLON) is down-regulated in acute myeloid leukemia and its knockdown attenuates neutrophil differentiation

BACKGROUND: Inhibitors of apoptosis (IAPs) were intensively investigated in the context of cancer where they promote tumor growth and chemoresistence. Overexpression of the IAP BIRC6 is associated with unfavorable clinical features and negatively impacts relapse-free survival in childhood acute myel...

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Detalles Bibliográficos
Autores principales: Schläfli, Anna M, Torbett, Bruce E, Fey, Martin F, Tschan, Mario P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514096/
https://www.ncbi.nlm.nih.gov/pubmed/23211188
http://dx.doi.org/10.1186/2162-3619-1-25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514096/
https://www.ncbi.nlm.nih.gov/pubmed/23211188
http://dx.doi.org/10.1186/2162-3619-1-25

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