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BIRC6 (APOLLON) is down-regulated in acute myeloid leukemia and its knockdown attenuates neutrophil differentiation
BACKGROUND: Inhibitors of apoptosis (IAPs) were intensively investigated in the context of cancer where they promote tumor growth and chemoresistence. Overexpression of the IAP BIRC6 is associated with unfavorable clinical features and negatively impacts relapse-free survival in childhood acute myel...
Autores principales: | Schläfli, Anna M, Torbett, Bruce E, Fey, Martin F, Tschan, Mario P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514096/ https://www.ncbi.nlm.nih.gov/pubmed/23211188 http://dx.doi.org/10.1186/2162-3619-1-25 |
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