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Clinical significance of E2F1 protein expression in non-small cell lung cancer

BACKGROUND: The transcription factor E2F1 has been implicated in cell cycle control and DNA damage response. Paradoxically, E2F1 can promote apoptosis and function as tumor suppressor. In non-small cell lung cancer (NSCLC), there are conflicting data for clinical significance of E2F1 expression. In...

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Detalles Bibliográficos
Autores principales: Hung, Jung-Jyh, Hsueh, Chung-Tsen, Chen, Kuan-Hua, Hsu, Wen-Hu, Wu, Yu-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514097/
https://www.ncbi.nlm.nih.gov/pubmed/23210897
http://dx.doi.org/10.1186/2162-3619-1-18