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Association of radiotherapy with preferential depletion of luminal epithelial cells in a BRCA1 mutation carrier

Radiation therapy (RT) after breast conservation therapy has recently been linked with significant reduction in risk of ipsilateral breast cancer among BRCA1 mutation carriers. However, the exact mechanism by which RT reduces incidence of BRCA1-associated cancer remains unclear. Here we studied fres...

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Detalles Bibliográficos
Autores principales: Chiang, Huai-Chin, Nair, Sreejith J, Yeh, I-Tien, Santillan, Alfredo A, Hu, Yanfen, Elledge, Richard, Li, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514114/
https://www.ncbi.nlm.nih.gov/pubmed/23210696
http://dx.doi.org/10.1186/2162-3619-1-31