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Prolonged FGF signaling is necessary for lung and liver induction in Xenopus

BACKGROUND: FGF signaling plays numerous roles during organogenesis of the embryonic gut tube. Mouse explant studies suggest that different thresholds of FGF signaling from the cardiogenic mesoderm induce lung, liver, and pancreas lineages from the ventral foregut progenitor cells. The mechanisms th...

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Detalles Bibliográficos
Autores principales: Shifley, Emily T, Kenny, Alan P, Rankin, Scott A, Zorn, Aaron M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514138/
https://www.ncbi.nlm.nih.gov/pubmed/22988910
http://dx.doi.org/10.1186/1471-213X-12-27