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AICAR inhibits ceramide biosynthesis in skeletal muscle

BACKGROUND: The worldwide prevalence of obesity has lead to increased efforts to find therapies to treat obesity-related pathologies. Ceramide is a well-established mediator of several health problems that arise from adipose tissue expansion. The purpose of this study was to determine whether AICAR,...

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Detalles Bibliográficos
Autores principales: Erickson, Katherine A, Smith, Melissa E, Anthonymuthu, Tamil S, Evanson, Michael J, Brassfield, Eric S, Hodson, Aimee E, Bressler, M Andrew, Tucker, Braden J, Thatcher, Mikayla O, Prince, John T, Hancock, Chad R, Bikman, Benjamin T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514253/
https://www.ncbi.nlm.nih.gov/pubmed/23134616
http://dx.doi.org/10.1186/1758-5996-4-45