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Crag Is a GEF for Rab11 Required for Rhodopsin Trafficking and Maintenance of Adult Photoreceptor Cells

Rhodopsins (Rhs) are light sensors, and Rh1 is the major Rh in the Drosophila photoreceptor rhabdomere membrane. Upon photoactivation, a fraction of Rh1 is internalized and degraded, but it remains unclear how the rhabdomeric Rh1 pool is replenished and what molecular players are involved. Here, we...

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Detalles Bibliográficos
Autores principales: Xiong, Bo, Bayat, Vafa, Jaiswal, Manish, Zhang, Ke, Sandoval, Hector, Charng, Wu-Lin, Li, Tongchao, David, Gabriela, Duraine, Lita, Lin, Yong-Qi, Neely, G. Gregory, Yamamoto, Shinya, Bellen, Hugo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514319/
https://www.ncbi.nlm.nih.gov/pubmed/23226104
http://dx.doi.org/10.1371/journal.pbio.1001438