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Longitudinal fluctuations in PD1 and PD-L1 expression in association with changes in anti-viral immune response in chronic hepatitis B

BACKGROUND: Controversy exists regarding the role of PD1 and its ligand PD-L1 in chronic hepatitis B infection. In some studies, persistent HBV infection has been attributed to high levels of PD-1 and PD-L1 expression on HBV-specific T-cells and antigen-presenting cells (APCs) respectively. Other st...

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Detalles Bibliográficos
Autores principales: Wenjin, Zhang, Chuanhui, Peng, Yunle, Wan, Lateef, Shaikh Abdul, Shusen, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514338/
https://www.ncbi.nlm.nih.gov/pubmed/22894700
http://dx.doi.org/10.1186/1471-230X-12-109