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Dok2 mediates the CD200Fc attenuation of Aβ-induced changes in glia

BACKGROUND: The interaction between the membrane glycoprotein, CD200 and its cognate receptor CD200 receptor (CD200R), has been shown to play a role in maintaining microglia in a quiescent state. There is evidence of increased activation under resting and stimulated conditions in microglia prepared...

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Detalles Bibliográficos
Autores principales: Lyons, Anthony, Downer, Eric J, Costello, Derek A, Murphy, Niamh, Lynch, Marina A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514341/
https://www.ncbi.nlm.nih.gov/pubmed/22642833
http://dx.doi.org/10.1186/1742-2094-9-107