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SFRP2 and Slug Contribute to Cellular Resistance to Apoptosis in Hypertrophic Scars

Hypertrophic scars (HS) are skin disorders which occur after wounding and thermal injury. Our previous studies have suggested that secreted frizzled-related protein 2 (SFRP2) is involved in HS formation and that the suppression of SFRP2 promotes apoptosis of hypertrophic scar fibroblasts (HSFBs). Ho...

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Detalles Bibliográficos
Autores principales: Chen, Liang, Wang, Zhenxiang, Li, Shirong, Zhao, Guangjian, Tian, Maosheng, Sun, Zhicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514356/
https://www.ncbi.nlm.nih.gov/pubmed/23226515
http://dx.doi.org/10.1371/journal.pone.0050229