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Supporting conditional mouse mutagenesis with a comprehensive cre characterization resource

Full realization of the value of the loxP-flanked alleles generated by the International Knockout Mouse Consortium will require a large set of well-characterized cre-driver lines. However, many cre driver lines display excision activity beyond the intended tissue or cell type, and these data are fre...

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Detalles Bibliográficos
Autores principales: Heffner, Caleb S., Herbert Pratt, C., Babiuk, Randal P., Sharma, Yashoda, Rockwood, Stephen F., Donahue, Leah R., Eppig, Janan T., Murray, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514490/
https://www.ncbi.nlm.nih.gov/pubmed/23169059
http://dx.doi.org/10.1038/ncomms2186