Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy

Theory, simulations and experimental results have suggested an important role of internal friction in the kinetics of protein folding. Recent experiments on spectrin domains provided the first evidence for a pronounced contribution of internal friction in proteins that fold on the millisecond timesc...

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Detalles Bibliográficos
Autores principales: Borgia, Alessandro, Wensley, Beth G., Soranno, Andrea, Nettels, Daniel, Borgia, Madeleine B., Hoffmann, Armin, Pfeil, Shawn H., Lipman, Everett A., Clarke, Jane, Schuler, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514500/
https://www.ncbi.nlm.nih.gov/pubmed/23149740
http://dx.doi.org/10.1038/ncomms2204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514500/
https://www.ncbi.nlm.nih.gov/pubmed/23149740
http://dx.doi.org/10.1038/ncomms2204

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