Cargando…

Complex DNA repair pathways as possible therapeutic targets to overcome temozolomide resistance in glioblastoma

Many conventional chemotherapeutic drugs exert their cytotoxic function by inducing DNA damage in the tumor cell. Therefore, a cell-inherent DNA repair pathway, which reverses the DNA-damaging effect of the cytotoxic drugs, can mediate therapeutic resistance to chemotherapy. The monofunctional DNA-a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoshimoto, Koji, Mizoguchi, Masahiro, Hata, Nobuhiro, Murata, Hideki, Hatae, Ryusuke, Amano, Toshiyuki, Nakamizo, Akira, Sasaki, Tomio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2012
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514620/ https://www.ncbi.nlm.nih.gov/pubmed/23227453 http://dx.doi.org/10.3389/fonc.2012.00186

Ejemplares similares

Clinical implications of microRNAs in human glioblastoma
por: Mizoguchi, Masahiro, et al.
Publicado: (2013)

Expression of stem cell marker and receptor kinase genes in glioblastoma tissue quantified by real-time RT-PCR
por: Yoshimoto, Koji, et al.
Publicado: (2011)

MicroRNAs in Human Malignant Gliomas
por: Mizoguchi, Masahiro, et al.
Publicado: (2012)

Radiation-induced spinal cord glioblastoma with cerebrospinal fluid dissemination subsequent to treatment of lymphoblastic lymphoma
por: Kikkawa, Yuichiro, et al.
Publicado: (2013)

Long-Term Hearing Outcome After Retrosigmoid Removal of Vestibular Schwannoma
por: Nakamizo, Akira, et al.
Publicado: (2013)

Current trend in treatment of glioblastoma in Japan: a national survey using the diagnostic procedure combination database (J-ASPECT study-glioblastoma)
por: Funakoshi, Yusuke, et al.
Publicado: (2021)

Precise Detection of IDH1/2 and BRAF Hotspot Mutations in Clinical Glioma Tissues by a Differential Calculus Analysis of High-Resolution Melting Data
por: Hatae, Ryusuke, et al.
Publicado: (2016)

ACT-16 THE POTENTIAL OF HYPOFRACTIONATED RADIOTHERAPY AND BEVACIZUMAB FOR GLIOBLASTOMA TREATMENT
por: Hata, Nobuhiro, et al.
Publicado: (2019)

Add-on bevacizumab can prevent early clinical deterioration and prolong survival in newly diagnosed partially resected glioblastoma patients with a poor performance status
por: Hata, Nobuhiro, et al.
Publicado: (2017)

Update on Chemotherapeutic Approaches and Management of Bevacizumab Usage for Glioblastoma
por: Funakoshi, Yusuke, et al.
Publicado: (2020)

Spinal endodermal cyst resembling an arachnoid cyst in appearance: Pitfalls in intraoperative diagnosis of cystic lesions
por: Kikkawa, Yuichiro, et al.
Publicado: (2012)

Current Trends and Healthcare Resource Usage in the Hospital Treatment of Primary Malignant Brain Tumor in Japan: A National Survey Using the Diagnostic Procedure Combination Database (J-ASPECT Study-Brain Tumor)
por: YOSHIMOTO, Koji, et al.
Publicado: (2016)

ACT-02 Changes in Recurrence Pattern and Prognosis of Glioblastoma after Approval of Bevacizumab as First-line Application
por: Funakoshi, Yusuke, et al.
Publicado: (2020)

Mesenchymal glioblastoma-induced mature de-novo vessel formation of vascular endothelial cells in a microfluidic device
por: Amemiya, Takeo, et al.
Publicado: (2021)

Deferred radiotherapy and upfront procarbazine–ACNU–vincristine administration for 1p19q codeleted oligodendroglial tumors are associated with favorable outcome without compromising patient performance, regardless of WHO grade
por: Hata, Nobuhiro, et al.
Publicado: (2016)

Supramaximal Resection Can Prolong the Survival of Patients with Cortical Glioblastoma: A Volumetric Study
por: OTSUJI, Ryosuke, et al.
Publicado: (2023)

Ankle-Brachial Index and Cardio-Ankle Vascular Index as Predictors of Cognitive Decline Over Time After Carotid Endarterectomy
por: Miyamatsu, Yuichiro, et al.
Publicado: (2022)

Metabolic remodeling of pyrimidine synthesis pathway and serine synthesis pathway in human glioblastoma
por: Nakamizo, Akira, et al.
Publicado: (2022)

Clinical significance of CDKN2A homozygous deletion in combination with methylated MGMT status for IDH‐wildtype glioblastoma
por: Funakoshi, Yusuke, et al.
Publicado: (2021)

Volumetric study reveals the relationship between outcome and early radiographic response during bevacizumab-containing chemoradiotherapy for unresectable glioblastoma
por: Takigawa, Kosuke, et al.
Publicado: (2021)

Potential Strategies Overcoming the Temozolomide Resistance for Glioblastoma
por: JIAPAER, Shabierjiang, et al.
Publicado: (2018)

Pediatric Glioma: An Update of Diagnosis, Biology, and Treatment
por: Funakoshi, Yusuke, et al.
Publicado: (2021)

Upregulation of Relaxin after Experimental Subarachnoid Hemorrhage in Rabbits
por: Kikkawa, Yuichiro, et al.
Publicado: (2014)

Liquid biopsy with multiplex ligation-dependent probe amplification targeting cell-free tumor DNA in cerebrospinal fluid from patients with adult diffuse glioma
por: Otsuji, Ryosuke, et al.
Publicado: (2022)

MPC-06 Cutting-edge of Cancer Genomic Medicine for brain tumors
por: Mizoguchi, Masahiro, et al.
Publicado: (2020)

IM-03 CD206 expression in peripheral blood-derived induced-microglia-like cells as a surrogate biomarker for the specific immune microenvironment of glioma
por: Hata, Nobuhiro, et al.
Publicado: (2020)

Preoperative Prediction of Intracranial Meningioma Grade Using Conventional CT and MRI
por: Amano, Toshiyuki, et al.
Publicado: (2022)

Nanomedicine-based combination therapies for overcoming temozolomide resistance in glioblastomas
por: Wang, Chun, et al.
Publicado: (2023)

Base-resolution methylomes of gliomas bearing histone H3.3 mutations reveal a G34 mutant-specific signature shared with bone tumors
por: Sangatsuda, Yuhei, et al.
Publicado: (2020)

Inhibition of Carbonic Anhydrase 2 Overcomes Temozolomide Resistance in Glioblastoma Cells
por: Zhao, Kai, et al.
Publicado: (2021)

Giant cranial angiolipoma with arteriovenous fistula: A case report
por: Hatae, Ryusuke, et al.
Publicado: (2022)

Metformin and temozolomide, a synergic option to overcome resistance in glioblastoma multiforme models
por: Valtorta, Silvia, et al.
Publicado: (2017)

Mifepristone Overcomes Tumor Resistance to Temozolomide Associated with DNA Damage Repair and Apoptosis in an Orthotopic Model of Glioblastoma
por: Llaguno-Munive, Monserrat, et al.
Publicado: (2018)

Molecular diagnosis of diffuse glioma using a chip-based digital PCR system to analyze IDH, TERT, and H3 mutations in the cerebrospinal fluid
por: Fujioka, Yutaka, et al.
Publicado: (2021)

Inhibition of DNA Repair in Combination with Temozolomide or Dianhydrogalactiol Overcomes Temozolomide-Resistant Glioma Cells
por: Ohba, Shigeo, et al.
Publicado: (2021)

eGFR and deep white matter hyperintensity as predictors of cognitive decline long after carotid endarterectomy
por: Nakamizo, Akira, et al.
Publicado: (2019)

LGG-20. CLINICAL FEATURES AND TREATMENT RESULTS FOR PEDIATRIC OPTICO-HYPOTHALAMIC ASTROCYTOMA
por: Yoshimoto, Koji, et al.
Publicado: (2020)

MV1035 Overcomes Temozolomide Resistance in Patient-Derived Glioblastoma Stem Cell Lines
por: Malacrida, Alessio, et al.
Publicado: (2022)

TBIO-08. BASE-RESOLUTION METHYLOMES OF GLIOMAS BEARING HISTONE H3.3 MUTATIONS REVEAL A G34 MUTANT-SPECIFIC SIGNATURE SHARED WITH BONE TUMORS
por: Sangatsuda, Yuhei, et al.
Publicado: (2020)

HGG-24. HIGH-GRADE GLIOMA WITH A NOVEL FUSION GENE OF VCL-ALK
por: Yamamoto, Shunsuke, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_h0f3sgt0g8me4fb8e3lj1otjms