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Novel roles for KLF1 in erythropoiesis revealed by mRNA-seq

KLF1 (formerly known as EKLF) regulates the development of erythroid cells from bi-potent progenitor cells via the transcriptional activation of a diverse set of genes. Mice lacking Klf1 die in utero prior to E15 from severe anemia due to the inadequate expression of genes controlling hemoglobin pro...

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Detalles Bibliográficos
Autores principales: Tallack, Michael R., Magor, Graham W., Dartigues, Benjamin, Sun, Lei, Huang, Stephen, Fittock, Jessica M., Fry, Sally V., Glazov, Evgeny A., Bailey, Timothy L., Perkins, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514668/
https://www.ncbi.nlm.nih.gov/pubmed/22835905
http://dx.doi.org/10.1101/gr.135707.111