Contributions of mRNA abundance, ribosome loading, and post- or peri-translational effects to temporal repression of C. elegans heterochronic miRNA targets

miRNAs are post-transcriptional regulators of gene activity that reduce protein accumulation from target mRNAs. Elucidating precise molecular effects that animal miRNAs have on target transcripts has proven complex, with varied evidence indicating that miRNA regulation may produce different molecula...

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Detalles Bibliográficos
Autores principales: Stadler, Michael, Artiles, Karen, Pak, Julia, Fire, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514671/
https://www.ncbi.nlm.nih.gov/pubmed/22855835
http://dx.doi.org/10.1101/gr.136515.111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514671/
https://www.ncbi.nlm.nih.gov/pubmed/22855835
http://dx.doi.org/10.1101/gr.136515.111

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