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An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations

Developing an understanding of the mechanism of voltage-gated ion channels in molecular terms requires knowledge of the structure of the active and resting conformations. Although the active-state conformation is known from x-ray structures, an atomic resolution structure of a voltage-dependent ion...

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Detalles Bibliográficos
Autores principales: Vargas, Ernesto, Yarov-Yarovoy, Vladimir, Khalili-Araghi, Fatemeh, Catterall, William A., Klein, Michael L., Tarek, Mounir, Lindahl, Erik, Schulten, Klaus, Perozo, Eduardo, Bezanilla, Francisco, Roux, Benoît
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514734/
https://www.ncbi.nlm.nih.gov/pubmed/23183694
http://dx.doi.org/10.1085/jgp.201210873