Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal trafficking

Mutations in small integral membrane protein of lysosome/late endosome (SIMPLE) cause autosomal dominant, Charcot-Marie-Tooth disease (CMT) type 1C. The cellular function of SIMPLE is unknown and the pathogenic mechanism of SIMPLE mutations remains elusive. Here, we report that SIMPLE interacted and...

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Detalles Bibliográficos
Autores principales: Lee, Samuel M., Chin, Lih-Shen, Li, Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514783/
https://www.ncbi.nlm.nih.gov/pubmed/23166352
http://dx.doi.org/10.1083/jcb.201204137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514783/
https://www.ncbi.nlm.nih.gov/pubmed/23166352
http://dx.doi.org/10.1083/jcb.201204137

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