Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion

The molecular underpinnings of synaptic vesicle fusion for fast neurotransmitter release are still unclear. Here, we used a single vesicle–vesicle system with reconstituted SNARE and synaptotagmin-1 proteoliposomes to decipher the temporal sequence of membrane states upon Ca(2+)-injection at 250–500...

Descripción completa

Detalles Bibliográficos
Autores principales: Diao, Jiajie, Grob, Patricia, Cipriano, Daniel J, Kyoung, Minjoung, Zhang, Yunxiang, Shah, Sachi, Nguyen, Amie, Padolina, Mark, Srivastava, Ankita, Vrljic, Marija, Shah, Ankita, Nogales, Eva, Chu, Steven, Brunger, Axel T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2012
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514886/
https://www.ncbi.nlm.nih.gov/pubmed/23240085
http://dx.doi.org/10.7554/eLife.00109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514886/
https://www.ncbi.nlm.nih.gov/pubmed/23240085
http://dx.doi.org/10.7554/eLife.00109

Ejemplares similares