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Variance in Epistasis Links Gene Regulation and Evolutionary Rate in the Yeast Genetic Interaction Network

Organisms face a constantly shifting landscape of environmental conditions and internal physiological states. How gene regulation and cellular functions are maintained across genetic and environmental variation is therefore a fundamental question in biology. Here, we analyze the Saccharomyces cerevi...

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Detalles Bibliográficos
Autores principales: Fierst, Janna L., Phillips, Patrick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514962/
https://www.ncbi.nlm.nih.gov/pubmed/23019067
http://dx.doi.org/10.1093/gbe/evs083