SP Transcription Factor Paralogs and DNA-Binding Sites Coevolve and Adaptively Converge in Mammals and Birds

Functional modification of regulatory proteins can affect hundreds of genes throughout the genome, and is therefore thought to be almost universally deleterious. This belief, however, has recently been challenged. A potential example comes from transcription factor SP1, for which statistical evidenc...

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Detalles Bibliográficos
Autores principales: Yokoyama, Ken Daigoro, Pollock, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514965/
https://www.ncbi.nlm.nih.gov/pubmed/23019068
http://dx.doi.org/10.1093/gbe/evs085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514965/
https://www.ncbi.nlm.nih.gov/pubmed/23019068
http://dx.doi.org/10.1093/gbe/evs085

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