Disentangling evolutionary signals: conservation, specificity determining positions and coevolution. Implication for catalytic residue prediction

BACKGROUND: A large panel of methods exists that aim to identify residues with critical impact on protein function based on evolutionary signals, sequence and structure information. However, it is not clear to what extent these different methods overlap, and if any of the methods have higher predict...

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Detalles Bibliográficos
Autores principales: Teppa, Elin, Wilkins, Angela D, Nielsen, Morten, Buslje, Cristina Marino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515339/
https://www.ncbi.nlm.nih.gov/pubmed/22978315
http://dx.doi.org/10.1186/1471-2105-13-235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515339/
https://www.ncbi.nlm.nih.gov/pubmed/22978315
http://dx.doi.org/10.1186/1471-2105-13-235

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