CTGF Increases IL-6 Expression in Human Synovial Fibroblasts through Integrin-Dependent Signaling Pathway

BACKGROUND: Connective tissue growth factor (CTGF; also known as CCN2) is an inflammatory mediator, and shows elevated levels in regions of severe injury and inflammatory diseases. CTGF is abundantly expressed in osteoarthritis (OA). However, the relationship between CTGF and IL-6 in OA synovial fib...

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Detalles Bibliográficos
Autores principales: Liu, Shan-Chi, Hsu, Chin-Jung, Chen, Hsien-Te, Tsou, Hsi-Kai, Chuang, Show-Mei, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515445/
https://www.ncbi.nlm.nih.gov/pubmed/23227240
http://dx.doi.org/10.1371/journal.pone.0051097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515445/
https://www.ncbi.nlm.nih.gov/pubmed/23227240
http://dx.doi.org/10.1371/journal.pone.0051097

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